Botanical Aspects of Phaseolus vulgaris

Common names: Common bean, White Kidney bean - Phaseolus vulgaris belongs to the botanical family of Leguminosae. It is a sub-erect or twining annual herb, native of tropical America and now grown extensively throughout the warm regions of the world. The kidney beans leaves are trifoliate; flowers white to violet-purple; pods slender, 10-26 cm long, straight or slightly curved, the surface glabrous or faintly pubescent, the beak prominent. Seeds are more or less kidney shaped, elongated or nearly globular, or somewhat compressed; white, red, purple blackish or mottled in appearance.

Varieties of the white common bean have been classified variously; some classifications are based on morphological characters of the plant, pod and seeds, while others are based on their mode of use.

Phytochemistry
The seeds of Phaseolus vulgaris contain an inhibitor of alpha-amylase. This alpha amylase inhibitor is identified in the protein fraction of the bean. This protein binds with the active sites of alpha- amylase and prevents the starch metabolizing activity; hence it is also called  “Starch Blocker” or “Carbohydrate blocker”.

The alpha-amylase inhibitor from Phaseolus vulgaris is a protein composed of two glycosylated protomers of 30 kDa, which are cleaved into two polypeptides of 16 and 14 kDa, respectively.

Mechanism of “carbohydrate blocking” action
The alpha-amylase inhibitors are also called “Carbo blockers” and these compounds are not directly involved in the weight loss process. However, the carbo blockers are indirectly helpful in weight loss due to inhibition of sugar assimilation, through inhibiting starch breakdown. With reduced amount of amylase available for break down, the complex carbohydrate has a better chance of travelling through the body without being assimilated, and is eventually excreted from the body instead of being converted into storage fat. An animal model study revealed that amylase inhibitors alter the amount and pattern of food intake and reduce weight gain probably through inducing satiety and increasing carbohydrate delivery to the distal (farthest) part of the small intestine in rats.

Health benefits of carbohydrate blockers
An alpha-amylase inhibitor inhibits the digestion of starch and carbohydrates thereby potentially improving postprandial carbohydrate tolerance in people with low glucose tolerance. As excess dietary carbohydrate is metabolized to fat; inhibition of carbohydrate digestion may help in weight management as well.

A partially purified white bean amylase inhibitor was found to reduce starch digestion and inactivate intraduodenal amylase in humans by 94 to 99.9%.16 The authors of this study reported that perfusion of the partially purified inhibitor (2.0, 3.5 or 5 mg/ml at the rate of 5 ml/min) into the duodenum of humans rapidly inhibited alpha-amylase activity in a dose-dependent manner. The inhibitor also inactivated intralieal and salivary amylase in vitro studies. Additionally, the specific activity of the inhibitor was not affected by exposure to gastric juice and was only minimally affected by exposure to duodenal juice.

In studies in normal subjects and in patients with diabetes mellitus, a purified amylase inhibitor from beans was found to exert a “starch blockade” effect. In comparison with the placebo, ingestion of this inhibitor with 50 g starch substantially reduced post-prandial increases in plasma concentrations of glucose and insulin in both normal subjects and those with diabetes.

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Overweight during holidays? Get back on track

Welcome back! Your friends have just given you a warm welcome from your holidays; you are telling them how you enjoyed yourself; the beautiful places you have visited; the mouth watering delicacy you have tasted, the delicious food you have eaten, and obviously the extra kilos you have discovered on peeping half-heartedly at the mirror on returning home. It’s only normal that on returning from the holidays the bathroom-scales will cause some alarm. Even though you may feel less stressed and have even managed to stick to a correct and varied diet, it is still possible that your figure has gone astray.

Back to resolutions: as from tomorrow a strict diet and off to the gym! Great! Even though more than a month will be necessary to recover the perfect figure you had the very first day you strolled down to the beach this summer. Losing weight will entail sacrifices, ways and means, and time, which is not always available when returning home from the holidays.

ALTA CARE Laboratoires has launched on the market ALTADRINE Fat Burning Tablets.  Extracts of Citrus aurantium (synephrine) and Guarana` (caffeine) help in the burning of fat deposits in a natural way. Yes……we are talking of fat deposits. A correct and varied diet may help you in stopping the accumulation of further kilos, but not the elimination of the fat deposits accumulated during the holidays. Eliminating this excess is nowadays very simple. The alternatives range from physical exercise – so if you intend going to the gym by all means do so – to having some food supplement that will help you recover your correct weight. ALTADRINE Fat Burner Tablets is the solution to your problem; it’s a specific product that contains extracts that are capable of burning your surplus fat while producing an energy available for all the body. The active ingredients are in fact capable of acting directly on fatty cells, stimulating the metabolism of the fat and reducing those fats that make you look away from a mirror. Combining ALTADRINE Fat Burner Tablets with a well-balanced and varied diet, and maybe even some sport, will definitely speed up the process of fat-burning, and thus recover within a short time the figure that is to your liking.

If sacrifices send shivers down your spine and if  time is not available for sport; or if the sporting activity is not enough to lose weight quickly, ALTADRINE Fat Burner will be of enormous help. Two tablets a day (morning and evening) with a large glass of water for 21 days will be enough to obtain the first results; then if necessary repeat the cycle after a pause of seven days. Bid farewell to your guilt conscience; during the holiday you have satisfied your appetite and desires. Great! That’s what holidays are for.

Now get hold of a box of ALTADRINE Fat Burner and a glass of water, and even if you have no intention of going to the gym, ALTA CARE Laboratoires still recommends a well-balanced and varied diet in order to obtain the best results in the shortest time possible.

For more information visit: www.altacare.com

Get in Shape in Time for Christmas with Altadrine Fat Burner

Christmas is just around the corner! You and your friends are making plans for the festivities…what to wear and what not to wear.  You have already spotted the dress of your dreams, but there is a problem…how to get in it!  With just a couple of weeks to go it seems already impossible to control your weight and yet you will be tempted once again to eat more during the festivities!  Not to mention the alcohol intake.. However Altadrine can keep your weight under control…

ALTA CARE Laboratoires has launched on the market ALTADRINE Fat Burning Tablets.  Extracts of Citrus aurantium (synephrine) and Guarana` (caffeine) help in the burning of body fat deposits in a natural way. Yes……we are talking of body fat deposits. A correct and varied diet may help you in stopping the accumulation of further kilos, but not the elimination of the fat deposits accumulated during the holidays. Eliminating this excess is nowadays very simple. The alternatives range from physical exercise – so if you intend going to the gym by all means do so – to having some food supplement that will help you recover your correct weight. ALTADRINE Fat Burner Tablets is the solution to your problem; it’s a specific product that contains extracts that are capable of burning your surplus fat while producing an energy available for all the body. The active ingredients are in fact capable of acting directly on fatty cells, stimulating the metabolism of the fat into energy and reducing those fats that make you look away from a mirror. Combining ALTADRINE Fat Burner Tablets with a well-balanced and varied diet, and maybe even some sport, will definitely speed up the process of fat-burning, and thus recover within a short time the figure that is to your liking.

If sacrifices send shivers down your spine and if  time is not available for sport; or if the sporting activity is not enough to lose weight quickly, ALTADRINE Fat Burner will be of enormous help. Two tablets a day (morning and evening) with a large glass of water for 21 days will be enough to obtain the first results; then if necessary repeat the cycle after a pause of seven days.

Now get hold of a box of ALTADRINE Fat Burner and a glass of water, and even if you have no intention of going to the gym, ALTA CARE Laboratoires still recommends a well-balanced and varied diet in order to obtain the best results in the shortest time possible.

For more information visit: www.altacare.com

Altadrine Fat and Carb Blocker with white kindney bean extract

  Altadrine Fat & Carb blocker is an alpha-amylase inhibitory natural extract obtained from Phaseolus vulgaris (common bean, white kidney bean) that blocks the digestion of carbohydrates and dietary starch, thereby offering potential benefits in the maintenance of healthy blood sugar levels and optimal body composition. Carbohydrate blocking is important for the control of healthy blood sugar levels and is also important to control the correct insulin level.

The emergence of obesity as the leading public health problem in Europe and the USA is a matter of great concern. Over 58 million adults in the U.S. are obese and about one in five American children and adolescents is overweight. Obesity greatly increases the risk of premature death, and it is a major risk factor for developing chronic conditions such as diabetes, heart disease, high blood pressure, gallbladder disease, arthritis, lung problems and some of the more common forms of cancer. According to government statistics, obesity accounts for about three hundred thousand premature deaths in the United States each year.

The increased incidence of obesity is attributed to improper diet and a sedentary lifestyle. Therefore the quality of our lives depends upon appropriate lifestyle choices. One has to shed down excess weight if one wants to lead a healthy life with no complications. Reduction of fat storage / overweight of individuals requires much and prolonged effort. Diet restrictions and extreme exercise regimens have poor success rates in weight reduction. However, smart nutritional choices supplemented with natural weight management products in combination with appropriate exercise regimens would serve the purpose.

Excess carbohydrates in the diet are ultimately converted to fats and stored in the body. In both plants and animals, starch is broken down by enzymes known as amylases and maltase to yield glucose. Plants break down starch during seed germination or tuber sprouting to supply the energy and carbon skeletons. Animals and fungi break down plant starch to obtain glucose for their own metabolism. The enzymes that catalyze the conversion of starch (a polysaccharide) into sugar molecules (monosaccharides) are called amylases. Surprisingly, plants usually contain amylase inhibitory compounds in the same organs (seeds and tubers) where the starch is stored, to ward off bacterial, fungal and animal predators. No parallels exist in mammalian systems.

Alta Care Laboratoires focuses interest on the amylase inhibitors produced by plants to block amylase activity in the human digestive tract. A carbohydrate blocker with an amylase inhibitor acts as an anti nutrient that obstructs the digestion of starch and absorption of glucose. Therefore amylase inhibitors are therapeutically valued in conditions such as diabetes (to reduce blood sugar levels) and in weight management. One of the conventionally used drugs in the management of diabetes, Acarbose, is a complex oligosaccharide that delays the digestion of ingested carbohydrates, thereby resulting in a smaller rise in blood glucose concentration following food intake. Acarbose inhibits the action of pancreatic amylase in breaking down starch, thereby achieving this effect.

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