Botanical Aspects of Phaseolus vulgaris

Common names: Common bean, White Kidney bean - Phaseolus vulgaris belongs to the botanical family of Leguminosae. It is a sub-erect or twining annual herb, native of tropical America and now grown extensively throughout the warm regions of the world. The kidney beans leaves are trifoliate; flowers white to violet-purple; pods slender, 10-26 cm long, straight or slightly curved, the surface glabrous or faintly pubescent, the beak prominent. Seeds are more or less kidney shaped, elongated or nearly globular, or somewhat compressed; white, red, purple blackish or mottled in appearance.

Varieties of the white common bean have been classified variously; some classifications are based on morphological characters of the plant, pod and seeds, while others are based on their mode of use.

Phytochemistry
The seeds of Phaseolus vulgaris contain an inhibitor of alpha-amylase. This alpha amylase inhibitor is identified in the protein fraction of the bean. This protein binds with the active sites of alpha- amylase and prevents the starch metabolizing activity; hence it is also called  “Starch Blocker” or “Carbohydrate blocker”.

The alpha-amylase inhibitor from Phaseolus vulgaris is a protein composed of two glycosylated protomers of 30 kDa, which are cleaved into two polypeptides of 16 and 14 kDa, respectively.

Mechanism of “carbohydrate blocking” action
The alpha-amylase inhibitors are also called “Carbo blockers” and these compounds are not directly involved in the weight loss process. However, the carbo blockers are indirectly helpful in weight loss due to inhibition of sugar assimilation, through inhibiting starch breakdown. With reduced amount of amylase available for break down, the complex carbohydrate has a better chance of travelling through the body without being assimilated, and is eventually excreted from the body instead of being converted into storage fat. An animal model study revealed that amylase inhibitors alter the amount and pattern of food intake and reduce weight gain probably through inducing satiety and increasing carbohydrate delivery to the distal (farthest) part of the small intestine in rats.

Health benefits of carbohydrate blockers
An alpha-amylase inhibitor inhibits the digestion of starch and carbohydrates thereby potentially improving postprandial carbohydrate tolerance in people with low glucose tolerance. As excess dietary carbohydrate is metabolized to fat; inhibition of carbohydrate digestion may help in weight management as well.

A partially purified white bean amylase inhibitor was found to reduce starch digestion and inactivate intraduodenal amylase in humans by 94 to 99.9%.16 The authors of this study reported that perfusion of the partially purified inhibitor (2.0, 3.5 or 5 mg/ml at the rate of 5 ml/min) into the duodenum of humans rapidly inhibited alpha-amylase activity in a dose-dependent manner. The inhibitor also inactivated intralieal and salivary amylase in vitro studies. Additionally, the specific activity of the inhibitor was not affected by exposure to gastric juice and was only minimally affected by exposure to duodenal juice.

In studies in normal subjects and in patients with diabetes mellitus, a purified amylase inhibitor from beans was found to exert a “starch blockade” effect. In comparison with the placebo, ingestion of this inhibitor with 50 g starch substantially reduced post-prandial increases in plasma concentrations of glucose and insulin in both normal subjects and those with diabetes.

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Get in Shape in Time for Christmas with Altadrine Fat Burner

Christmas is just around the corner! You and your friends are making plans for the festivities…what to wear and what not to wear.  You have already spotted the dress of your dreams, but there is a problem…how to get in it!  With just a couple of weeks to go it seems already impossible to control your weight and yet you will be tempted once again to eat more during the festivities!  Not to mention the alcohol intake.. However Altadrine can keep your weight under control…

ALTA CARE Laboratoires has launched on the market ALTADRINE Fat Burning Tablets.  Extracts of Citrus aurantium (synephrine) and Guarana` (caffeine) help in the burning of body fat deposits in a natural way. Yes……we are talking of body fat deposits. A correct and varied diet may help you in stopping the accumulation of further kilos, but not the elimination of the fat deposits accumulated during the holidays. Eliminating this excess is nowadays very simple. The alternatives range from physical exercise – so if you intend going to the gym by all means do so – to having some food supplement that will help you recover your correct weight. ALTADRINE Fat Burner Tablets is the solution to your problem; it’s a specific product that contains extracts that are capable of burning your surplus fat while producing an energy available for all the body. The active ingredients are in fact capable of acting directly on fatty cells, stimulating the metabolism of the fat into energy and reducing those fats that make you look away from a mirror. Combining ALTADRINE Fat Burner Tablets with a well-balanced and varied diet, and maybe even some sport, will definitely speed up the process of fat-burning, and thus recover within a short time the figure that is to your liking.

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Now get hold of a box of ALTADRINE Fat Burner and a glass of water, and even if you have no intention of going to the gym, ALTA CARE Laboratoires still recommends a well-balanced and varied diet in order to obtain the best results in the shortest time possible.

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